LoNG graduate student Ethan Whitman describes associations between DunedinPACE, a novel epigenetic measure of biological aging, and measures of brain structure. Importantly, the associations replicate in three independent cohorts.

LoNG Research Associate Annchen Knodt evaluates test-retest reliability of principal FC gradient measures, finding good reliability as well as associations with aging and cognition.

Professor Hariri, along with Professor Tim Strauman, discusses how examination of intrinsic macroscale brain organization, as reflected in the principal FC gradient, can extend and enrich investigations of self-regulation and depression.

LoNG graduate student Ethan Whitman examines cortical functional topography using fMRI in the Dunedin Study, finding associations with IQ and gait speed.

LoNG research associate Annchen Knodt presents findings of reduced structural brain integrity in members of the Dunedin Study with a long history of cannabis use, but patterns are explained by their propensity to use other substances as well.

Check out the latest from LoNG collaborator Christina Carlisi on the structural brain correlates of lifecourse-persistent antisocial behavior, this time looking at subcortical volumes, published in Development and Psychopathology.

We've demonstrated that commonly used task fMRI measures are not reliable enough for individual differences research or clinical translation. Our latest Trends in Cognitive Sciences review focuses on what we can do to work towards generating fMRI measures that are.

LoNG graduate student Maria Gehred explores links between prospective and retrospective measures of childhood maltreatment and structural brain integrity at midlife.

To aid efforts to identify early life interventions for mitigating risk for dementia, LoNG graduate student Tracy d'Arbeloff explores possible links between white matter integrity and fitness and healthy lifestyle behaviors in midlife.

LoNG graduate student Max Elliott reports on disparities in the pace of aging at midlife. This study is made possible by the efforts of many individuals over many years to collect high quality measures of 19 biomarkers indexing the cardiovascular, metabolic, renal, immune, detal, and pulmonary systems in Dunedin Study members across adulthood and into midlife. Check it out in Nature Aging!

LoNG collaborator Dr. Leah Richmond-Rakerd demonstrates that as adults, children with better self-control aged more slowly, showed fewer signs of brain aging, and were more equipped to manage later-life health, financial, and social demands.

This week in JAMA, LoNG and colleagues report associations between childhood lead exposure and mid-life measures of brain integrity, as well as cognitive decline. Read about the study in Duke Today or check out the report in JAMA.

Now published in AJP: cortical thinning is a transdiagnostic feature of general psychopathology. Also check out the editor's spotlight on the article!

A new LoNG study published in Psychological Science points to the unreliability of task-fMRI, and its unsuitability for individual differences research. Read more on APS News or Duke Today.

Nature News discusses ongoing efforts to understand general psychopathology, including work by the LoNG.

A study led by LoNG collaborator Christina Carlisi finds associations between life-course-persistent antisocial behavior and cortical surface area and thickness. Read more about it on BBC News or The Guardian.

Learn more about brain-age from our study published in Molecular Psychiatry.

Published in Brain Communications: white matter hyperintensities are present in mid-life, and already predict cognitive decline.

Published in Molecular Psychiatry: replicability of structural brain alterations associated with general psychopathology.

Learn more about gait speed from our study published in JAMA.

Check out Dr. Hariri's commentary in Neuron, "The emerging importance of the cerebellum in broad risk for psychopathology."

Check out the latest publication by LoNG grad student Max Elliott, demonstrating how shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks.

Check out iHeartRadio and 23andMe's new podcast about the cultural influences of DNA testing.

In the Duke Magazine special issue on fear, Professor Hariri comments on fear and the brain.

Congrats to grad student Adrienne Romer on her successful PhD defense!

LoNG grad student Max Elliott finds that transdiagnostic risk for mental illness maps onto hyper-connectivity between visual association cortex and networks supporting executive control and self-referential processes. Read about it in Duke Today, New England Journal of Medicine's Psychiatry Watch, The Chronicle, or check out the full paper or commentary in Biological Pyschiatry.

Congrats to grad student Matt Scult on his successful PhD defense!

Episode 5: "You're Not Alone" of the Audible original podcast What Were You Thinking features commentary from Professor Hariri on how changes in the adolescent brain can lead to violence. Check it out!

Head over to Duke Today, Forbes, Psychology Today, or The Herald Sun to read about LoNG grad student Matt Scult's work published today in Cerebral Cortex.

A New York Times article features Professor Hariri's research into the amygdala.

LoNG postdoc Reut Avinun finds that increased reward-related ventral striatum activity is associated with a weaker link between sleep disturbances and depression in the DNS. Read more in Duke Today, Express, or Live Science.

LoNG postdoc Justin Kim shows that a link between corticolimbic structrual connectivity and trait anxiety is influenced by BDNF genotype and sex.

LoNG postdoc Justin Kim celebrates his graduation from Dartmouth with advisor Dr. Paul Whalen!

LoNG graduate student Adrienne Romer is awarded the Association for Psychological Science's Student Research Award!

The LoNG links structural differences in cerebellar circuity with general risk for mental illness. Read about the findings at Psychology Today or Duke Today.

The LoNG has moved from the Sociology/Psychology building on Duke's West Campus to the Grey Building at 2020 West Main St.

This month's issue of Biological Psychiatry features work from the LoNG on a common variant in a Williams Syndrome gene as well as a corresponding editorial piece.

The LoNG scans its final DNS participant, for a total of 1330!

The University of Otago in NZ, where the LoNG and colleagues will scan the brains of the 1000 Dunedin Longitudinal Study participants, comments on the launch of the study.

LoNG graduate student Matt Scult links activity in the prefrontal cortex during computation in working memory with the ability to regulate emotion.

The LoNG has collaborated with the LaBar Lab to map spontaneous emotional states in the brain during resting-state fMRI. Read more on Duke Today.

LoNG collaborator 23andMe publicly releases its Genotyping Services for Research. See Dr. Hariri's comments and more at The Verge.

The LoNG identifies an epigenetic and brain pathway linking low socioeconomic status to depression, published this month in Molecular Psychiatry.

With some help from Duke Engineering, the LoNG printed out a 3D model of Professor Hariri's brain from an MRI scan!

For several years, the LoNG has partnered with the consumer genetics firm 23andMe for genotyping study participants. Now the company is slated for a full launch of this service for researchers everywhere. See Dr. Hariri's comments and more at GenomeWeb.

The Washington Post covers new research on treating depression, mentioning work from the LoNG.

Professor Hariri co-authors a Nature Neuroscience review with Andrew Holmes discussing translational stress research.

The American Psychological Association gives a glowing review of Professor Hariri's textbook, Looking Inside the Disordered Brain.

The LoNG publishes more on how fear and reward circuitry can interact to predict stress-related problem drinking. Click the button below to see the publication, or check out Duke's press release covering this as well as the lab's findings on sexual risk behavior.

Amygdala & ventral striatum reactivity interact to predict gender-specific sexual risk behavior - check out former graduate student Liz Victor's findings!

Check out the the trailer for Genetic Me, a documentary by Danish science journalist Lone Frank, including appareances by Professor Hariri. Release date in the US TBA.

Check out the Huffington Post's coverage of LoNG postdoctoral researcher Johnna Swartz's finding that amygdala reactivity can predict future depressive symptoms, published in the journal Neuron (be sure to watch the video!). See additional coverage of the publication at Men's Health and other outlets.

LoNG postdoctoral researcher Johnna Swartz recently published in the American Journal of Psychiatry a finding that family history of depression and stressful life events may interact to influence risk for depression by altered development of amygdala reactivity during adolescence.

Watch a video about Duke's summer research program for undergraduate neuroscience majors, including Jacob Miller who worked in the LoNG in the 2014 Summer term.

LoNG alum and collaborator Justin Carre publishes new research on the effects of testosterone on neural reactivity to threat in men. Check out the local news coverage of the story.

Nature Neuorscience publishes a finding by LoNG postdoctoral researcher Yuliya Nikolova on how DNA methylation predicts the brain's response to threat. Check out Duke's press release of the story or the paper in Nature Neuroscience.

Professor Hariri is selected as a Thomson Reuters Highly Cited Researcher!

The Duke Neurogenetics Study celebrates the completion of its 1000th participant!

Listen to Professor Hariri and other Duke faculty discuss neuroscience and the law on WUNC's "The State of Things" radio program.

Head over to the Washington Post to see what Professor Hariri has to say about a recent study published in Psychological Science.

Actor & director Alan Alda explores the intersections between neuroscience and the criminal justice system in his two-part PBS series, Brains on Trial. Check out Part 1 and Part 2 of the series, or watch as Professor Hariri and other experts at Duke continue the discussion with Alan and hold a question and answer session on the topic.

Check out the article on Professor Hariri and the Duke Neurogenetics Study in the Spring issue of Duke Alumni Magazine!

Check out the press release in the UK, read Discover magazine's blog about it, or listen to the CBS news radio clip.

In the spirit of the season, we carved a pumpkin and posed it for the three stages of the Duke Neurogenetics Study. It was a hit!

Take a look at this recent news piece about our scientific collaborator, 23andMe.

Listen to Professor Hariri discuss the Duke Neurogenetics Study on a radio program exploring scientific work in the Research Triangle.

Can regulating a specific enzyme help treat anxiety disorders in people? Check out Professor Hariri's comments in the latest issue of Scientific American.

Check out this article in the May 2012 issue of Discover magazine for a glimpse of the Duke Neurogenetics Study and Professor Hariri's work.

The Laboratory of NeuroGenetics is featured in the November/December 2011 issue of Duke IGSP's periodical.

Professor Hariri comments on findings in the amygdalae of Dutch combat soldiers.

Get to know Professor Hariri and the LoNG.

Professor Hariri comments on a new study on a possible biomarker of risk for PTSD in women.

Professor Hariri is co-Editor-in-Chief of the new journal Biology of Mood and Anxiety Disorders. Learn more about this exciting new outlet for the best research in the field.

In the latest issue of The Scientist, Professors Hariri and Whalenreview how our evolving understanding of the amygdala will lead to new strategies for treating and predicting psychopathology. In a companion report at F1000 they provide additional details about how different psychological, biological, and genetic factors can influence the sensitivity of the amygdala to give rise to differences in behavior between individuals.

Read the editor's comments
Get to know the authors

Professor Hariri comments on neural correlates of anxiety in an article published by the Dana Foundation.

Justin is included in the 2010 - 2011 Both Sides of the Brain profiles, which highlight his investigation of hormonal involvement in competition, a combination of his dual-passion for neuroscience and hockey.

Science highlights new research, including a study by Professor Hariri & colleagues, suggesting that chronic loneliness can cause changes in the cardiovascular, immune, and nervous systems.

Patrick Fisher is highlighted as a scholar of the Blueprint-funded Multimodal Neuroimaging Training Program (MNTP).

Watch lectures by Professor Hariri and other leading scientists at the Genes & Environment: Finding the Missing Heritability of Complex Traits conference held at Stanford University on October 14 & 15, 2010

Research by partners Terrie Moffitt and Avshalom Caspi have open new means to understand how genes interact with our environment.

Adam returns from his worldly travels. He thought that his trip was to Cambodia, but he was surprised to find himself on the set of "Legends of the Hidden Temple." Regardless, he had a good time, and the Nickelodeon network has recruited him as the new host of the hit show. Adam will continue to work in the lab, however he takes his new role very seriously! You just don't mess with the Hidden Temple!

Adam Makes a New, Very Large, Friend
Legends of the Hidden Temple

ScienceNow reports on a study published in Nature that used FDG-PET in a large single-family pedigree of rhesus monkeys to estimate the heritability of brain regions shaping the expression of anxious temperament. Professor Hariri provides expert commentary and compares these findings to the LoNG's ongoing imaging genetics research.

DukeMed Magazine features a story on the challenges of diagnosing, treating, and living with anxiety in modern times. Professor Hariri provides expert commentary and analysis.

LoNG collaborator, Dr. Peter Gianaros, is featured in an article reviewing the impact of social disadvantage on the brain.

Curious about why that food dehydrator on late night TV is so tempting? NPR's Morning Edition discusses the influence of dopamine and its receptors on trait impulsivity. This report comes from a new study in Science that links dopamine autoregulation and impulsivity. Listen to Professor Hariri's comments.

ScienceNOW Daily News discusses new research that points to the potential involvement of the BDNF gene in modulating fear circuitry. Professor Hariri provides expert commentary and analysis.

The Science-Business eXchange discusses the 5HT-1A autoreceptor and current research on its relationship to anxiety and depression. Professor Hariri provides expert commentary and analysis.

The Gene-Environment Conference took place at the Sanford Institute for Public Policy on May 18th and 19th, 2009. View the interesting talks online from Professors Rutter, Moffitt, Caspi, Hariri, and others pertaining to interactions between genes, brains, and behavior.

The Neuroscience of Emotion Conference took place at Tufts University, June 4-6, 2009.

Is Your Investing Personality in Your DNA? Jason Zweig of The Wall Street Journal visits Professor Hariri’s laboratory to find out if his genes and brain activity help to shape his behavior.